Chorea as a Rare Manifestation of Neuropsychiatric Systemic Lupus Erythematosus: a Case Report

  • Qurat ul ain District Head Quarters Hospital, Jhelum, Pakistan.
  • Afsheen Ishfaq Fazaia Ruth Pfau Medical College/PAF Hospital, Karachi, Pakistan
  • Farzana Kouser NDC Medical Center, Islamabad, Pakistan
  • Rabia Rasool District Head Quarters Hospital, Jhelum, Pakistan.
Keywords: Chorea, Systemic lupus erythematosus, ANA, Anti-Smith

Abstract

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multisystemic involvement. It has variable clinical presentations and a relapsing and remitting course. Clinical manifestations are broad, ranging from mild mucocutaneous involvement to major organ involvement. We present a case of a 32-year-old female with repeated movements of the right arm, and confusion with a background of pains in multiple joints. She was diagnosed as a case of Neuropsychiatric Systemic Lupus Erythematosus (NPSLE). She was managed with pulse therapy of cyclophosphamide (CYC) along with other supportive medications. After six months of intensive immunosuppressive therapy, she remained well and continued maintenance therapy.

Author Biographies

Afsheen Ishfaq, Fazaia Ruth Pfau Medical College/PAF Hospital, Karachi, Pakistan

Assistant Professor, Department of Medicine

Farzana Kouser, NDC Medical Center, Islamabad, Pakistan

Medical Specialist

Rabia Rasool, District Head Quarters Hospital, Jhelum, Pakistan.

Department of Medicine,

Published
2025-08-02