Anti-CASPR 2 antibody encephalitis: a case report

Maryam Khalil; Zaid Waqar; Hira Badar Abbasi; Amina Saddiqa; Bushra Khalid; Soban khan

doi:10.56310/pjns.v18i03.262

Maryam Khalil Pakistan Institute of Medical Sciences, Islamabad
Zaid Waqar Pakistan Institute of Medical Sciences, Islamabad
Hira Badar Abbasi Pakistan Institute of Medical Sciences, Islamabad
Amina Saddiqa Pakistan Institute of Medical Sciences, Islamabad
Bushra Khalid Pakistan Institute of Medical Sciences, Islamabad
Soban khan Pakistan Institute of Medical Sciences, Islamabad

DOI: https://doi.org/10.56310/pjns.v18i03.262

Keywords: CASPR 2, autoimmune encephalitis, KV1, autoimmunity

Abstract

Encephalitis is a term denoted to Inflammation in the brain which can be due to infection, autoimmunity, or can be a part of a paraneoplastic phenomenon with malignancy. Anti-CASPR 2 antibody encephalitis is a rare form of encephalitis that can be associated with malignancy, paraneoplastic phenomenon or can be an autoimmune disease. We present a case of a young boy who presented with new onset seizures and altered sensorium and was diagnosed with anti-CASPR 2 antibody encephalitis. Anti-CASPR 2 Antibody Encephalitis is a rare form of encephalitis which due to its great diverse presentation should be kept in the differential diagnosis of conditions like limbic encephalitis.