Post Moderna Vaccine associated acute disseminated encephalomyelitis (ADEM) - A case report.

  • Sajid Khan Pakistan Institute of Medical Sciences
  • Soban Khan
  • Zaid Waqar Pakistan Institute of Medical Sciences
  • Hafsa Mobeen
  • Naveed Khan
  • Muhammad Hassan
Keywords: acute disseminated encephalomyelitis (ADEM), Covid 19, Moderna


Due to pervasive pandemic of SARS CoV-2 the reports of rare neurological complications have turned up out of the ordinary. The public health concerns are raised due to SARS-CoV-2 infection and vaccinations as this recent pandemics has set the development and deployment of vaccines at large scale. The randomized controlled trials being carried were underpowered to foresee these rare adverse effects. Amongst other neurological complications acute disseminated encephalomyelitis ADEM has been reported with vaccination for SARS-CoV-2. Herein, we report a patient with a unique presentation of ADEM, a severe neuroinflammatory disorder developed shortly after mRNA based Moderna vaccine for SARS-CoV-2.